ka Mea huna NUI ia Lapaʻau NUI manaʻo ʻoe he naʻaupō loa ʻoe e hoʻomaopopo!
ʻO nā lāʻau lapaʻau, nā ʻiole, ka DNA, a me ka palaho ʻo Big Pharma
Hoʻololi:
heluhelu mai o
. . .
E nānā hou aku
[Heluhelu kūhelu: 2 kumu] [Palapala hoʻokolokolo kūhelu: 1 kumu] [Pololei mai ke kumu: 1 kumu] [Nā mana kiʻekiʻe a me nā pūnaewele hilinaʻi: 2 kumu]Ma mua palekana a maikaʻi hoʻi, i kēia manawa make. No ke aha i hoʻomanaʻo ʻia ai ka nui o nā lāʻau?
By Richard Ahern - Pono mākou e hilinaʻi makapō he palekana a maikaʻi nā lāʻau āpau no ka mea ke ʻōlelo nei ka FDA? Pono mau ka ʻepekema ma hope o ka ʻoihana lāʻau?
Ma 2022, ʻo ia nā nīnau koʻikoʻi a mākou e nīnau ai!
Ma kēia ʻatikala, e pane mākou i kēlā mau nīnau koʻikoʻi.
Ke noho nei mākou i kahi manawa i ʻike ʻole ʻia o a popilikia honua i ka wā ʻaʻole i ʻoi aku ka manaʻo o ka nīnau e pili ana i ka maikaʻi o ka lāʻau lapaʻau. He nui ka poʻe o mākou e nīnau i ka palekana o nā lāʻau lapaʻau, nā lāʻau lapaʻau, a me nā lāʻau lapaʻau, akā ʻo ka loaʻa ʻana o nā hōʻike paʻakikī e kākoʻo i kekahi mea ʻaneʻane hiki ʻole i kahi lālā o ka lehulehu.
ʻO ka ʻoiaʻiʻo, aia mākou i kēia manawa i kēlā me kēia manawa e aʻa ai kekahi e nīnau i ka pono o ka lāʻau lapaʻau a i ʻole ka palekana o ka lāʻau lapaʻau, he mea maʻamau ka ʻike ʻana i kēlā kanaka i pāpā ʻia no ka "hoʻolaha ʻana i ka ʻike hewa" ma ka pāpaho pūnaewele.
Ke ʻae ʻia kahi lāʻau lapaʻau e ka FDA, nā aupuni a me nā ʻO Big Tech e koi mai ʻaʻole mākou e nīnau i kona palekana. ʻO ka poʻe aʻa e nīnau i ka "ʻepekema" o ka hoʻāʻo ʻana i ka lāʻau lapaʻau i kapa ʻia he poʻe kipi kipi.
A ʻo ...
He 12,787 ka nui o nā hoʻomanaʻo lāʻau i hoʻopuka ʻia e ka FDA mai ka makahiki 2012.
Ma ka awelika, hoʻomanaʻo ʻia nā lāʻau 1,279 i kēlā me kēia makahiki. Ke alakaʻi nei ʻo ʻAmelika i ke ala me ka hoʻomanaʻo he 12,028, ʻo ka ʻāina me ka lua o ka hoʻomanaʻo nui ʻana ʻo Kanada, me ka liʻiliʻi o 554 mau lāʻau hoʻomanaʻo.
Pono kēlā mau helu e haʻalulu iā ʻoe i kou kumu, kēlā me kēia o kēlā Hoʻomanaʻo ʻo FDA he "whoops, kala mai mākou i hoʻopau ʻia" e ka FDA.
Kuhi ʻia kēia ʻatikala e wehewehe i ke kumu o ka nui o ka hoʻomanaʻo ʻana i ka lāʻau.
ʻOi aku ka laulā o kēia ʻatikala e manaʻo e hōʻike ʻaʻole ʻoe "anti-science" inā nīnau ʻoe i ka ʻepekema ma hope o ka hoʻāʻo lāʻau.
ʻAʻole kēia he manaʻo kipi, he ʻoiaʻiʻo kēia i paʻi ʻia i ka ʻepekema a Big Pharma i kahili ma lalo o ka moena.
ʻO ka ʻike hoʻopilikia i hōʻike ʻia ma lalo nei ua kāohi ʻia e ke kaiāulu ʻepekema a ʻaʻole hiki ke ʻike ʻia ia mea ma ka media mainstream. ʻO ka mea pōʻino, no ka mea, ʻo ka ʻepekema ma hope o ka hoʻāʻo ʻana i nā lāʻau lapaʻau e pono ai ka ʻike kūpono o ka biology, ʻaʻole i ka haʻi ʻana i kekahi manaʻo, ʻaʻole paha ka hapa nui o ka poʻe nūpepa i ka ʻike, makaʻu loa, a i ʻole ka palaualelo e hōʻike aku. He mea paʻakikī kēia i ka lehulehu ke hoʻomaopopo i ka mea e pili ana, ʻo ia ke kumu i noho lōʻihi ai kēia ʻike i ka malu.
Eia kekahi, ʻo ke kumu hewa loa ʻo ka ʻoiaʻiʻo e pili ana i ke ʻano o ka hoʻāʻo ʻana i nā lāʻau lapaʻau e hōʻino iā Big Pharma no ka mea ke kānalua nei i ka palekana o nā kaukani lāʻau. nā lāʻau āpau, a me nā lāʻau lapaʻau i "ʻae ʻia" no ka hoʻohana kanaka. Ma ke koʻikoʻi, hiki iā mākou ke ʻike i kahi hoʻoikaika loiloi hou o kēia mau lāʻau lapaʻau me kahi helu nui e hoʻomanaʻo ʻia.
Ua lawa anei ʻo Big Pharma e kau i ke olakino ma mua o ka loaʻa kālā?
Paʻakikī!
A hiki i ka wā e ʻike nui ʻia ai kēia hemahema make me ka palekana o ka lāʻau lapaʻau, ʻaʻole paha mākou e ʻike i ka hana ʻana, akā na ka poʻe i ʻike e hoʻomau i ka hoʻōho no ia mea a hiki i nā hui lāʻau lapaʻau ke hāʻawi i nā hōʻoia paʻa ua hoʻoponopono ʻia a aia nā hana kūpono. wahi e pale ai i nā pilikia e hiki mai ana.
ʻO mākou i Ola hoʻohiolo e hoʻomālamalama i kēia ʻike a hana i ke ʻano e hiki ai i nā mea a pau ke hoʻomaopopo, ʻaʻohe mea o kou ʻike ʻepekema. Manaʻo mākou e hiki ke loaʻa kēia ʻike i nā mea a pau, me ka ʻole o nā huaʻōlelo ʻepekema, no laila ma hope o ka heluhelu ʻana i kēia e hoʻomaopopo pono ʻoe i nā pilikia me ka hoʻāʻo ʻana i ka lāʻau a me ka palekana lāʻau.
Pilikia nā ola…
I ka pōkole, pili kēia ʻike i kahi kīnā genetic i nā rodents lab, ma muli paha o ka hānau pio ʻana, ʻo ia hoʻi, ʻaʻole kūlohelohe ke ʻano o ka launa pū ʻana me nā lāʻau lapaʻau. ʻOi aku ka mea nui, hoʻāla kēia i nā kānalua e pili ana i nā hoʻāʻo lāʻau lapaʻau āpau i nā holoholona i hānai ʻia i loko o nā labs.
Mākaukau ʻoe e aʻo i ka manaʻo o Big Pharma he naʻaupō loa ʻoe e hoʻomaopopo?
Ua ʻae ʻia nā lāʻau lapaʻau FDA i hoʻomanaʻo ʻia
E hahai i ka ʻepekema
ʻEhia mau manawa āu i lohe ai i nā luna aupuni e ʻōlelo nei "e hahai i ka ʻepekema" i ka wā e pili ana i ka lāʻau lapaʻau a olaʻo pono?
No laila, e “hahai i ka ʻepekema”!
Eia ka ʻike wikiwiki o ka biology ma hope o ka mea a mākou e kamaʻilio nei, inā ʻoe i mākaukau mua i kēia. e kala i keia pauku, akā he mea koʻikoʻi ke kua i ka pilikia koʻikoʻi o ka palekana olakino.
E luʻu kākou i loko…
E lawe i kahi keena mai kou kino a nānā iā ia ma lalo o kahi microscope ikaika. E ʻike ʻoe i ke kino kelepona nui me kahi puʻupuʻu liʻiliʻi i loko, i kapa ʻia ʻo ka cell nucleus. Aia i loko o ka nucleus kāu DNA, kāu moʻomeheu piha a kū hoʻokahi e hoʻopaʻa inoa no "ʻoe".
ʻO DNA ke code no ke ola.
Hoʻopili ʻia ka DNA a pelu ʻia i mau chromosomes. Hoʻokaʻawale ʻia nā Chromosomes i nā ʻāpana o ka DNA i kapa ʻia ʻo genes, a hoʻoholo kēlā me kēia gene i kahi ʻano kikoʻī. Aia nā haneli a hiki i nā tausani o nā genes i kēlā me kēia chromosome.
E noʻonoʻo wale i ka nucleus ma ke ʻano he hale waihona puke (kahi mea liʻiliʻi me 46 mau puke no ke kanaka); ʻO nā chromosomes nā puke pākahi, a ʻo nā genes nā paukū ma ia mau puke.
Makemake nā kānaka ʻepekema i nā mea i hoʻonohonoho pono ʻia, no laila ua helu lākou i kēlā me kēia pālua o nā chromosomes. No ka hāʻawi ʻana iā ʻoe i kekahi mau laʻana, loaʻa i ka chromosome pair one kahi gene e hoʻoholo ai i ka nui o kou lolo. Loaʻa i nā chromosomes sex (pair 23) nā genes e hoʻoholo ai i kāu kāne.
Loaʻa i nā kānaka he 23 mau chromosomes a he 46 ka nui.
Loaʻa i nā ʻano like ʻole nā helu o nā chromosomes. Eia kekahi laʻana, he 20 mau ʻiole o nā ʻiole a he 40 ka huina o nā ʻiole.
E hoʻomanaʻo, ua ʻili wale ʻia nā chromosomes i nā ʻāpana DNA ...
ʻO ka DNA e pili ana i nā ʻano o ke kino, ua kapa ʻia ʻo coding DNA no ka mea e hoʻopaʻa inoa ʻo ia no nā protein e hana ai i kēlā mea ola (ua hana ʻia mākou me nā protein). Hoʻopili nā genes i ka DNA. Inā pōʻino ka coding DNA, hiki iā ia ke hōʻeha nui i ke kino no ka mea ua hana ʻia nā protein hewa.
E hoʻomanaʻo mai ka papa biology e māhele mau ana nā cell?
I kēlā me kēia manawa e puʻunaue ai ke kelepona, pono ia e kope i ka DNA a pau i loko o kona nucleus. I ka wā mahele pūnaewele, pono e pale ʻia ka coding DNA no ka pale ʻana i nā hoʻololi weliweli.
E pili pū me aʻu, hiki koke mai kēia!
ʻAʻole nā code DNA āpau no nā protein, aia pū kekahi DNA non-coding ʻaʻole code no kekahi mea; nolaila ua kapa pinepine ia ʻōpala DNA.
ʻAʻole pono ka DNA Junk!
Hoʻokumu ʻia nā ʻaoʻao o nā chromosomes me ka DNA junk a ua kapa ʻia nā telomere. Mālama ʻo Telomeres i ka DNA coding o nā chromosomes mai ka pōʻino i ka wā o ka mahele cell.
Kiʻi i kēia:
ʻO ke ʻano a me ka hana o nā telomeres ua like ia me ka hopena plastik o kahi kaula kāmaʻa e pale ai i ka haki ʻana.
Ua like nō hoʻi nā Telomeres me ka fuse ma ka pōkā.
Ua like lākou me ka fuse no ka mea i kēlā me kēia manawa e māhele ai ke kelepona a kope ʻia kona mau chromosomes e nalowale ana kahi hapa liʻiliʻi o kāna DNA. He hopena ʻaoʻao hiki ʻole ke pale ʻia kēia o ka mīkini ma hope o ka hoʻopiʻi DNA. No laila, pili pono ka telomere a me ka lōʻihi; I ko mākou mau makahiki, ua maloʻo a pōkole nā telomeres, akā mālama ʻia ka ʻāpana DNA coding o ka chromosome.
Nā pēpē loaʻa nā telomere lōʻihi, akā ʻoi aku ka pōkole o ka poʻe ʻelemakule. ʻO nā telomere lōʻihi ke kuleana no ka ʻōpio a me ka hoʻoponopono ʻana i ka ʻiʻo wikiwiki.
He aha ka telomere? - Telomeres a me ka ʻelemakule
Telomeres a me ka maʻi kanesa
Pili pū ka lōʻihi o Telomere a me ke kanesa.
Hiki i kēlā me kēia keena ke hoʻokaʻawale a hana hou i kāna DNA i nā manawa liʻiliʻi ma mua o ka pau ʻana o nā telomeres (ua puhi ʻia ka fuse) - i kēia manawa, ʻike ʻia ka DNA coding i kēia manawa. ʻIke ʻia kēia ʻo ka palena ʻo Hayflick. Hiki i ka hapa nui o nā pūnaewele ke puʻunaue ma kahi o 40-60 mau manawa ma mua o ka hiki ʻana i kēia palena.
Ke hoʻomaka ka pōʻino o ka DNA coding, hiki ke hoʻololi i nā hoʻololi pōʻino i hiki ke hopena i ka maʻi kanesa inā hoʻomau ka puʻunaue.
No ka pale ʻana i kēia, loaʻa i nā cell kahi "mechanical control damage" i hoʻopaʻa ʻia iā lākou mai ka māhele ʻana i ka wā i pau ai ka telomere fuse. Kapa ʻia kēia hana kenekulia. I ka wā e lilo ai ke kelepona i mea ʻelemakule, hoʻōki ia i ka māhele ʻana a ʻaʻohe mea e hana, ua like ia me ka "zombie cell".
ʻO ia wale nō ka hapalua o ka moʻolelo…
He mea nui nō hoʻi e hoʻomaopopo i ka hiki ke hoʻopōʻino ʻia ka coding DNA ma nā ʻano ʻē aʻe mai mutagens, e like me ka radiation ionizing, nā mea radioactive, a me kekahi mau kemika. Inā hōʻino ʻia ka DNA coding o ke kelepona mai kahi mutagen hiki ke lilo i ka maʻi kanesa. ʻO ka mea pōmaikaʻi, ʻo kāna palena Hayflick e pale iā ia mai ka hana hou ʻana, ʻo ia ka pale mai ka maʻi kanesa. Inā hiki i kahi pūnaewele me ka DNA coding pōʻino ke puʻunaue wale i 40-60 mau manawa, pale ia mai ka hana ʻana i kahi maʻi nui.
ʻO nā maʻi maʻi maʻi maʻi he mau pūʻulu me ka DNA coding pōʻino i hoʻomau i ka puʻunaue mau loa no ka mea ua pau ka hana pono ʻana o ka hana ʻino o ka senescence.
ʻO ke kūkulu ʻia ʻana o nā cell senescent ka mea e ʻelemakule ai ka ʻiʻo. ʻO kahi laʻana, ʻo ke kūkulu ʻia ʻana o nā ʻili ʻili ʻulaʻula ka mea e alakaʻi ai i ka ʻili wrinkled a lahilahi i ka wā ʻelemakule. ʻOi aku ka nui o nā pūnaewele kahiko, ʻoi aku ka lohi o ka hoʻoponopono ʻana iā ia iho mai ka pōʻino no ka mea ʻaʻole hiki i nā pūnaewele kahiko ke māhele a hoʻololi iā lākou iho.
Ma nā ʻōlelo maʻalahi, loaʻa iā mākou kahi kālepa ma waena o ka ʻelemakule a me ke kanesa!
E hoʻomanaʻo, pili nā mea a pau i kēia:
ʻO ka ʻiʻo i hana ʻia me nā telomeres lōʻihi e lōʻihi ka makahiki a e hoʻōla hou mai ka pōʻino i ka wikiwiki. Eia nō naʻe, no ka mea hiki ke hoʻomau i ka māhele ʻana i kēia mau cell, hiki ke pilikia i ka maʻi kanesa no ka mea ʻaʻohe o lākou ʻano hana hoʻomalu pōʻino o kahi palena Hayflick.
Pehea ka pili ʻana o nā telomeres i ka ulu ʻana o ka maʻi kanesa?
ʻO ka PILIKIA me nā lāʻau lapaʻau - ʻO ka pilikia NUI
ʻAe, no ke aha e pili ai kekahi o kēia i ka palekana lāʻau?
Hele mai nā mea a pau i nā ʻiole…
ʻAe, nā ʻiole!
Ua manaʻo ka poʻe ʻepekema he mau telomere lōʻihi nā ʻiole āpau. Ua hōʻike ʻia e Kipling lāua ʻo Cooke i ka makahiki 1990 ua loaʻa i nā ʻiole "nā telomeres lōʻihi loa"ʻoi aku ka nui o ka nui ma mua o nā telomeres kanaka."
Ua pololei kā lākou ʻike akā eia ke kicker:
Ma luna o ʻelua mau makahiki i hala aku nei, ka mea olaola Ua kuhi ʻia ʻo Bret Weinstein ʻO nā telomere ultra-lōʻihi wale nō i loaʻa i nā ʻiole lab i hānai ʻia i ke pio ʻana, akā he mau telomere ka lōʻihi maʻamau nā ʻiole hihiu.
Ua pololei ʻo ia! He ʻike nui kēia!
Ua hōʻoia ʻia kēia ma kahi pepa e Greider and Hemann (2000), i ka wā i hoʻohālikelike ai lākou i ka lōʻihi telomere o nā ʻiole lab a me nā ʻiole hihiu. Ua hoʻoholo lākou "ʻoi aku ka pōkole o ka lōʻihi o Telomere i loko nā ʻano ʻano hihiu"!
Loaʻa i nā ʻiole lab nā telomeres lōʻihi loa.
Loaʻa i nā ʻiole hihiu nā telomere maʻamau.
Weinstein a me Ciszek i ʻōlelo ʻia ma ke kuhiakau hiki ke waiho (2002 pepa) ʻo kēia mau telomere ka lōʻihi loa he "hopena i manaʻo ʻole ʻia o ka hānau pio ʻana". Ua manaʻoʻiʻo lākou ʻo ke ʻano o ka hoʻoulu ʻana i nā ʻiole, e like me ka hoʻoulu ʻana i nā ʻiole i ka wā ʻōpio loa e hoʻonui i ka hua hānau (ua hoʻomaha ʻia nā ʻiole hānau ma 8 mau mahina) ua hoʻololi ʻia ka lōʻihi o ka telomere.
E hoʻomanaʻo mai ka wā ma mua ua like nā telomeres lōʻihi i ka hoʻoponopono ʻana i ka ʻiʻo wikiwiki?
ʻOiaʻiʻo, ʻo ia ka mea i ʻike ʻia ma nā ʻiole lab e like me ka hōʻike ʻana Alexander, P. (1966). Ua ʻōlelo lākou, "ʻO ka ʻoiaʻiʻo nui loa ʻo nā ʻiole kahiko loa (e like me ka ʻoi aku o 2.5 mau makahiki) i ka wā i pepehi ʻia ʻoiai ʻoi aku ka maikaʻi, he liʻiliʻi nā pathologies a aneane hiki ʻole ke ʻike ʻia mai nā holoholona ʻōpio" (i ka makahiki 1966 ua manaʻo ʻia ʻo ia ka hihia no nā ʻiole a pau).
ʻO kēia mau ʻiole lab i hānai ʻia i loko o ka noho pio ʻana he ʻōpiopio maoli nō, ua hoʻonui ʻia ka hiki ke hoʻoponopono i nā ʻiʻo i pohō, a ua kūpaʻa ʻole i ka ʻeha.
He mau ʻiole nui lākou! Akā aia hoʻokahi wahi hopu liʻiliʻi…
ʻO ka haʻahaʻa o kēia hiki ke hoʻoulu hou i nā cell, ʻo ia hoʻi, ua pilikia loa kēia mau ʻiole i ka maʻi kanesa no ka mea ʻaneʻane ʻaʻole i hiki i ko lākou mau cell i ka ʻelemakule! ʻAʻole i loaʻa iā lākou kēlā hana hoʻomalu pōʻino e pale ai i ka maʻi kanesa!
ʻO kēia mau ʻiole lab a pau, inā e ʻae ʻia e ola i ko lākou ola, ʻaʻole e make i ka wā ʻelemakule, akā, make lākou i ka maʻi kanesa.
Eia ka nūhou maikaʻi ʻole:
Ke hoʻohana ʻia nei kēia mau ʻiole genetically mutated i ka hoʻāʻo olakino a me ka noiʻi!
Inā hoʻāʻo ʻia ka lāʻau i hoʻopōʻino i ke kelepona i nā ʻiole lab, hiki ke ʻike ʻole ʻia kēlā pōʻino no ka mea hiki i nā ʻiole ke hoʻoponopono i ka ʻiʻo me ka wikiwiki ʻole. ʻO ka mea ʻē aʻe, ma muli o nā telomeres lōʻihi loa o nā ʻiole, ʻoi aku ka kiʻekiʻe o ko lākou maʻi kanesa.
Loaʻa iā mākou kahi kūlana o ka hoʻohaʻahaʻa ʻana i ka pōʻino o ke kino a me ka manaʻo nui o ka maʻi kanesa.
Ua hōʻuluʻulu maikaʻi ʻia kēia ma ka hopena o Weinstein a me Ciszek's (2002) pepa kahi i hōʻike ai lākou i kēia mau mea:
“No laila, pono mākou e noʻonoʻo hou i ka hoʻohana ʻana i nā mea i manaʻo ʻia he palekana no ka mea ʻaʻole lākou i pōʻino i nā 'iole'. I ka manawa like, hiki i ka hoʻāʻo palekana me nā ʻiole lab ke hoʻonui i ka nui o ka pilikia o ka maʻi kanesa, e alakaʻi ana i ka mālama pono ʻole e pili ana i kekahi mau mea waiwai.
ʻO ka mea pōʻino, ʻaʻohe mea i hoʻolohe, a kanu ʻia ka pepa e ka hui ʻepekema. Hiki i nā lāʻau lapaʻau ke hele i nā hoʻāʻo hoʻāʻo ʻana i nā rodent me nā waihoʻoluʻu lele inā ʻoiaʻiʻo hiki iā lākou ke hana i ka pōʻino nui o ke kino.
Aia paha kēia mau lāʻau i loko o kāu keʻena lāʻau lapaʻau!
E ʻeli hohonu kākou…
ʻO ka ʻike ʻia ʻana o kēia ʻano ʻano ʻino i loko o nā ʻiole lab, e like me ka mea i paʻi ʻia e Greider a me Hemann (2000) i loaʻa i nā ʻiole lab i hoʻolako ʻia e ka hale hana ʻo Jackson (JAX) ma ʻAmelika Hui Pū ʻIa. ʻO ka JAX lab kekahi o nā mea hoʻolako nui o ka honua i nā ʻiole lab i nā mea noiʻi ma ka honua holoʻokoʻa ʻAmelika Hui Pū ʻIa.
Akā eia kekahi mea hoihoi loa e noʻonoʻo ai…
Hiki ke hoʻopili pololei ʻia kēia ʻike i nā ʻiole lab JAX no ka mea ʻo lākou ka mea i hoʻāʻo ʻia e Greider lāua ʻo Hemann. Inā ʻo Jackson lab ʻiole wale nō nā ʻiole lab i hoʻomohala i kēia mau telomere ultra-lōʻihi, he wehewehe paha ia no ka helu kiʻekiʻe o ka hoʻomanaʻo ʻana i ka lāʻau lapaʻau ma ʻAmelika Hui Pū ʻIa, me ka ʻike ʻana ua hoʻolako ʻia ka hapa nui o nā mea noiʻi US e ka hale hana ʻo Jackson.
ʻOi loa:
Hoʻonui kēia i ka pilikia nui o nā protocol breeding i hoʻohana ʻia no nā mea āpau holoholona i hāʻawi ʻia i nā mea noiʻi. ʻO ka hoʻoulu ʻana i kēlā me kēia hanauna o kekahi ʻano i loko o kahi keʻena lab, kahi i loaʻa ʻole ai nā kaomi koho kūlohelohe e hopena paha i nā hoʻololi i manaʻo ʻole ʻia.
ʻO ka hope loa, ua hana ʻia ka hapa nui o nā lāʻau lapaʻau no ka hoʻohana kanaka. Ua ulu nā kānaka i nā kaukani makahiki i loko o ke kaiapuni kūlohelohe, ʻaʻole kahi hale hana.
ʻO ka hoʻāʻo ʻana i nā lāʻau lapaʻau ma luna o nā holoholona i hoʻomohala i nā hoʻololi kūlohelohe mai ka hoʻoulu ʻana o ka hale hoʻopaʻa pio he kumu hoʻohālike maikaʻi ʻole a weliweli no ka hoʻāʻo ʻana i ka lāʻau lapaʻau a me ke kano.
ʻAʻole loaʻa nā telomere ultra-lōʻihi loa i nā kānaka a ʻaʻohe o mākou mana palena ʻole no ka hoʻoponopono ʻana i ka ʻiʻo, akā ua hoʻāʻo ʻia kekahi o nā lāʻau lapaʻau a mākou e lawe nei me ka ʻike ʻole i nā holoholona e hana!
He ʻepekema popopo kēlā!
No ke aha ke kumu o ka ʻiole? - Nā pōmaikaʻi o ka hoʻāʻo ʻana i nā holoholona ma nā ʻiole liʻiliʻi
Ke nīnau nei paha ʻoe…
No ke aha he mea nui ka ʻiole ke hana ʻia ka hoʻāʻo ʻana i ka lāʻau lapaʻau holoholona ma luna o nā mammals nui?
He hoʻomaopopo maʻamau kēia. ʻO ka mea maʻamau, hoʻāʻo ʻia nā lāʻau lapaʻau āpau i nā ʻiole (a me nā ʻiole liʻiliʻi ʻē aʻe), a ʻoiai aia nā pilikia me ka hoʻohana ʻana i nā ʻiole i ka noiʻi, hāʻawi pū lākou i kahi pōmaikaʻi kūʻokoʻa i ka hoʻāʻo ʻana i ka palekana lāʻau.
Eia ke kumu:
ʻO nā holoholona liʻiliʻi like ua hoʻokē ʻai nā ʻiole i nā pōʻai ola ʻoi aku ka wikiwiki ma mua o nā holoholona nui a me nā kānaka. No ka hoʻokomo ʻana iā Dutta and Sengupta (2015) "ua ʻike ʻia hoʻokahi makahiki kanaka e like me ʻeiwa mau lā ʻiole".
Pono pono nā ʻiole no ka ʻimi ʻana i nā hopena lōʻihi o nā lāʻau lapaʻau e ʻike ʻia i nā holoholona nui.
ʻO ia ke kumu e pono ai ka hoʻāʻo holoholona!
I ka wā o ka hoʻāʻo ʻana i ka lāʻau lapaʻau, hāʻawi pinepine nā ʻepekema i nā koʻokoʻo liʻiliʻi i ka nui o nā lāʻau lapaʻau i ka manawa pōkole. ʻO ka manaʻolana, ʻo nā hopena ʻaoʻao paha ka mea e ʻike ʻia e ka holoholona a i ʻole ke kanaka i ka wā lōʻihi ma nā haʻahaʻa haʻahaʻa.
ʻAʻole naʻaupō kēia unuhi o nā hōʻike noiʻi mai nā holoholona a i ke kanaka, akā ma ke kumumanaʻo, hiki i nā rodents liʻiliʻi ke ʻae i nā ʻepekema e nānā i ka wā e hiki mai ana e ʻike i nā hopena lōʻihi o ka lāʻau lapaʻau.
E noʻonoʻo e pili ana…
E lawe i ka lāʻau e hōʻino mālie ai i ke kino a e lōʻihi nā makahiki. E ho'āʻo kēia i nā mammals nui aʻe akā hiki ke hāʻule i nā ʻiole no ka wikiwiki o ko lākou ola.
ʻO kēia kekahi o nā pōmaikaʻi nui o ka hoʻāʻo ʻana i nā holoholona i nā ʻiole liʻiliʻi, no ka mea, ʻo ia wale nō ke ala e uhuki ai i nā pōʻino lōʻihi i hana ʻia e nā lāʻau lapaʻau.
ʻO nā lāʻau lapaʻau e hōʻeha koke i nā ʻiole e hōʻike paha i kahi hōʻeha lōʻihi no nā kānaka a hiki i nā makahiki he nui ke hōʻike.
Hiki iā ʻoe ke lohe i kēia puʻupuʻu e kaomi pū ana i kēia manawa?
I ka loaʻa ʻana o nā telomeres lōʻihi loa i nā ʻiole lab a hiki ke hoʻoponopono i ka pōʻino o ke kelepona me ka wikiwiki loa, e hāʻule ke kumu hoʻohālike holoʻokoʻa o ka ʻike ʻana i nā hopena ʻaoʻao lōʻihi!
Hiki i nā lāʻau lapaʻau ke hoʻāʻo i nā ʻiole no ka mea hiki i nā ʻiole ke hoʻoponopono koke i ka pōʻino o ka cell no ka ʻike ʻana o nā ʻepekema.
A hiki wale i ka ʻae ʻia ʻana o kēlā lāʻau lapaʻau no ka hoʻohana ʻana i ke kanaka a ua lawe ka poʻe iā ia no nā makahiki he nui e hoʻomaka ai nā hopena ʻaoʻao lōʻihi. E wehewehe kēia i ke kumu e hoʻomanaʻo ʻia ai ka hapa nui o nā lāʻau i nā makahiki he nui ma hope o ka ʻae ʻia.
Ma ia manawa, ua lohi loa! Ua nalowale nā ola, ua hoʻomanaʻo ʻia ka lāʻau lapaʻau, a ʻōlelo ka FDA "oops"!
A laila hoʻi hou ka pōʻai!
Nā mea maikaʻi ʻole i ʻae ʻia e ka FDA - Nā hiʻohiʻona hauʻoli
Nui nā lāʻau lapaʻau FDA i manaʻo ʻia he palekana a maikaʻi hoʻi i ʻike ʻia he make.
He lōʻihi ka papa inoa o nā hemahema FDA akā eia kekahi mau hiʻohiʻona hauʻoli loa i hiki ke hoʻopili ʻia i nā anomalies genetic i ka hoʻāʻo ʻana i nā holoholona.
Eia kekahi o nā pōʻino lāʻau lapaʻau maikaʻi loa i ka mōʻaukala…
ʻO ka wehe ʻana o Cerivastatin
ʻO ka lāʻau i ʻai ola i nā kānaka:
ʻO kekahi o nā lāʻau lapaʻau FDA weliweli loa cerivastatin, i ʻike ʻia e kona inoa inoa ʻo Lipobay, he statin synthetic.
Ua kuhikuhi nui ʻia nā statins ma ka honua holoʻokoʻa e like me ka papa maʻamau o nā lāʻau lapaʻau i hoʻohana ʻia e hōʻemi i ka cholesterol i nā poʻe i pilikia i ka maʻi cardiovascular. Ma US, kaukaʻi mau nā kauka 200 miliona mau statins no kēlā me kēia makahiki.
Ua kūʻai ʻia ʻo Lipobay e ka hui lāʻau lapaʻau Bayer i ka hopena o 1990s. Ua hoʻihoʻi ʻia mai ka mākeke honua i ka makahiki 2001 ma muli o ka nui o nā mea make i hōʻike ʻia. Ua ʻike ʻia ʻo ka hapa nui o ka poʻe i make no ka make rhabdomyolysis ma muli o ka lāʻau. ʻO Rhabdomyolysis kahi maʻi weliweli i ke ola ma muli o ka haki ʻana o ka ʻiʻo ʻiʻo wikiwiki.
ʻO Lipobay ka mea i hoʻopau maoli i nā ʻiʻo o nā maʻi!
Ke wāwahi ʻia ka ʻiʻo ʻiʻo, hoʻokuʻu ʻo ia i kahi protein i kapa ʻia ʻo myoglobin i loko o ke koko e pono e wehe ʻia e nā puʻupaʻa. I ka nui, ʻaʻole hiki i nā puʻupaʻa ke kānana i ka myoglobin me ka wikiwiki, hiki ke hoʻopōʻino i ka puʻupaʻa, a i nā hihia koʻikoʻi, hiki ʻole i ka puʻupaʻa a make.
ʻO ka hapa nui o nā make ma waena o nā poʻe maʻi Lipobay ma muli o ka rhabdomyolysis a me ka hopena o ka hōʻole ʻana o ka puʻupaʻa. Ua ʻike ʻia ʻo ka rhabdomyolysis i hoʻokumu ʻia e nā statins 16 i nā manawa 80 ʻoi aku ka kiʻekiʻe no Lipobay i hoʻohālikelike ʻia me nā statins ʻē aʻe.
Pehea i hanaʻia ai kēia?
Hiki iā mākou ke noʻonoʻo wale, akā he mea kūpono ke hoʻoholo ʻaʻole i ʻike ʻia kēia haʻihaʻi wikiwiki i ka wā o nā holoholona a me nā hoʻāʻo kanaka. ʻAʻole i ʻike ʻia ka hopena make a hiki i nā makahiki ma hope o ka ʻae ʻia ʻana o Lipobay.
Ua holo mālie nā hoʻokolohua lapaʻau i ke kanaka no ka mea pōkole loa ka manawa e ʻike ai i kēia hopena. Eia nō naʻe, ua ʻike ʻia paha ka rhabdomyolysis i nā hoʻāʻo ʻiole ma muli o ko lākou holo wikiwiki ʻana.
ʻO ka mea pōʻino, ʻo nā ʻiole lab me nā telomere lōʻihi ʻole e hoʻōla hou i ka ʻiʻo ʻiʻo a me ka pōʻino puʻupaʻa me ka wikiwiki e ʻike ʻole ʻia kēia hopena ʻaoʻao.
Hiki paha ke pale ʻia kēia pōʻino inā hana ʻia nā hoʻokolohua holoholona ma luna o nā ʻiole "maʻamau" a ʻaʻole nā mutants i hana ʻia e ka lab?
Hoʻokahi wale nō laʻana, he nui a nui aʻe nā lāʻau lapaʻau FDA i hāʻule ʻole.
Vioxx hoʻopaʻapaʻa
Aia kahi papa inoa lōʻihi o nā lāʻau i hoʻomanaʻo ʻia ʻaʻole pono ke hele i ko lākou ala i ka mākeke.
ʻO kekahi o nā lāʻau hoʻomanaʻo kaulana loa ʻo rofecoxib, i ʻike mau ʻia ʻo ia ʻO Vioxx, he lāʻau anti-inflammatory nonsteroidal (NSAID) i hoʻohana ʻia e mālama i ka ʻāʻī a me ka ʻeha nui. Hoʻomanaʻo ʻia ʻo Vioxx ma muli o nā hōʻike o ka pōʻino naʻau i alakaʻi i ka piʻi nui o ka hōʻeha puʻuwai a me ka hahau ʻana.
Ua hōʻino paha ʻo Vioxx i nā ʻāpana he nui o ke kino akā ua ʻike ʻia ʻo ia ka pōʻino o ka puʻuwai no ka mea ʻaʻole hiki i nā puʻuwai ke hana hou.
Ua ʻike ʻia ka pōʻino o ka cell i hana ʻia e Vioxx i ka wā o nā hoʻokolohua rodent, akā no kekahi kumu, ʻaʻole i ʻike ʻia.
Hoʻomanaʻo ʻo Bextra
ʻO kahi lāʻau like me Vioxx ma ka papa inoa hoʻomanaʻo FDA valdecoxib, i ʻike nui ʻia e kona inoa inoa ʻo Bextra. E like me Vioxx, ʻo Bextra kekahi NSAID i hoʻohana ʻia no ka mālama ʻana i ka maʻi arthritis.
Ua ʻae ʻia ʻo Bextra i Nowemapa 2001 e ka FDA. Ua hoʻomanaʻo ʻia i ʻApelila 2005, kokoke ʻehā makahiki ma hope. Ua haʻi ka FDA i nā kumu o ka hoʻomanaʻo ʻana he "hiki ke piʻi aʻe ka pilikia no nā hanana koʻikoʻi cardiovascular (CV) koʻikoʻi" a me kahi "pilikia nui o nā hopena ʻili koʻikoʻi", me ka ʻO Stevens-Johnson maʻi.
ʻO ka hoʻomanaʻo ʻana o Bextra i hopena i ka uku kalaima nui loa o kēlā me kēia ʻano!
ʻO ka hui lāʻau lapaʻau Pono ʻo Pfizer e uku he $1.3 biliona hoʻopaʻi hewa no ka hōʻailona hewa ʻana i ka lāʻau "me ka manaʻo e hoʻopunipuni a hoʻopunipuni paha". Pono pū ʻo Pfizer e uku i $1 biliona i nā pohō kīwila.
E hoʻokuʻu wale i kēia ʻoiaʻiʻo ...
ʻO ka uku kalaima nui loa i uku ʻia ma ka mōʻaukala na kahi hui lāʻau!
Hoʻomanaʻo ʻo Rezulin
Aia ma ka papa inoa o nā hemahema FDA nui loa…
ʻO Troglitazone, inoa inoa ʻO ka Rezulin, ua hoʻohana ʻia no ka mālama ʻana i ka maʻi maʻi diabetes a ʻo ia kekahi hihia o ka lāʻau i hoʻopōʻino i ke kino. ʻO ka mea kūikawā, ua hana ʻo Rezulin i ka pōʻino o ka ate.
I ka hoʻomaka ʻana, ma hope o nā hōʻike he nui o ka hāʻule ʻana o ka ate i ka poʻe maʻi e lawe ana i ka lāʻau lapaʻau, ua hoʻopuka ka FDA i nā ʻōlelo aʻo e koi ana i ka nānā ʻana i kēlā me kēia mahina o nā pae enzyme ate i nā maʻi.
Pīhoihoi kēia:
ʻAʻole a hiki i ka make ʻana o kahi mea maʻi 55 makahiki i ka hāʻule ʻana o ka ate ma hope o ka lawe ʻana iā Rezulin ma ke ʻano o kahi noiʻi i nānā ʻia e ka National Institutes of Health (NIH) i nīnau ʻia inā lawa ka nānā ʻana i nā pae enzyme.
Ua hoʻokuʻu ka NIH i ka lāʻau mai ke aʻo ʻana, a ma hope koke iho, ua manaʻo kekahi epidemiologist FDA nāna i loiloi iā Rezulin e hiki ke hoʻopili ʻia i ka 430 o nā hemahema o ka ate. Ua ʻike lākou ua loaʻa i nā maʻi a 1,200 manawa ʻoi aku ka nui o ka pilikia o ke akepaʻa i ka wā e lawe ai i ka lāʻau.
Ma Malaki 21, 2000, ua hoʻomanaʻo hope ka FDA iā Rezulin ma hope o kona noho ʻana ma ka mākeke no ʻekolu makahiki.
Hiki paha ke pale ʻia ka wehe ʻana o Rezulin inā ʻike ʻia ka pōʻino o ke ake i ka wā o nā hoʻāʻo rodent?
ʻO kēia mau lāʻau lapaʻau he hōʻailona liʻiliʻi wale nō o kahi papa inoa lōʻihi o nā lāʻau lapaʻau FDA i hoʻomanaʻo ʻia i hoʻomanaʻo ʻia ma hope, akā hōʻike lākou i ka ʻae ʻia ʻana o nā lāʻau lapaʻau a laila hoʻomanaʻo ʻia i nā makahiki he nui ma hope (a he nui nā ola ma hope) i ka wā e hoʻomaka ai nā hopena ʻaoʻao lōʻihi e hānai i ko lākou ʻino. poʻo.
I kahi hāmole:
Hiki ke pale ʻia kekahi hanana pōʻino o ka lāʻau i hoʻomanaʻo ʻia ma muli o kekahi ʻano o ka pōʻino o ke kino/pepa i hiki ke pale ʻia inā i hana ʻia nā hoʻāʻo ʻiole ma nā ʻano maʻamau. Mai kahi hiʻohiʻona hoʻāʻo lāʻau lapaʻau, ʻo nā ʻiole a me nā ʻiole liʻiliʻi he waiwai waiwai akā inā he ʻano maoli lākou.
E ʻoi aku ka maikaʻi…
Pehea e pili ana i ka nui o nā lāʻau lapaʻau i hiki ke hoʻolei ʻia no ka mea ua ʻike ʻia lākou e hoʻonui ana i ka maʻi kanesa i nā ʻiole i hoʻomaka mua ʻia i ka maʻi kanesa!?
Manaʻo wau ʻaʻole mākou e ʻike i ka pane i kēlā nīnau.
Ua palekana anei nā lāʻau lapaʻau? - He aha kā mākou e hana ai i kēia manawa?
Akaka ka memo:
ʻO ke kaʻina holoʻokoʻa o ka loiloi ʻana i ka maikaʻi a me ka palekana o ka lāʻau he hewa nui. Popopo ka ʻepekema o ka ʻoihana lāʻau!
ʻOiai me ka ʻike ʻole i ka ʻepekema, ʻo ka nānā wale ʻana i ka nui o nā lāʻau lapaʻau FDA i hoʻomanaʻo ʻia i hoʻomanaʻo ʻia he hōʻike maopopo loa ua hewa kekahi mea.
ʻO ka mea kaumaha, aia maoli kahi papa inoa o nā lāʻau lapaʻau FDA i ʻae ʻia e pepehi a luku i nā ʻohana.
ʻAʻole pono e ʻōlelo, ua pōmaikaʻi nui ka ʻepekema i ka lāhui kanaka, akā ʻaʻole kūpono, a ʻoi aku paha ka pololei, ʻaʻole hemolele nā kānaka ʻepekema. ʻAʻole ʻo ka nīnau ʻepekema ʻaʻole ʻoe e "anti-science", e hoʻoikaika ʻoe i ka ʻepekema no ka mea ʻo ia ke ʻano o ka ʻepekema.
Nīnau nā kānaka ʻepekema i ka noiʻi mua, hana lākou i kahi kuhiakau a laila hoʻāʻo. No ka mea nohona Media, ʻO nā hui a me nā aupuni e kapa i ka poʻe "anti-science" ke nīnau lākou a olaʻo He pupule ka wehewehe ʻana. ʻO ia ka "anti-science"!
Ua manaʻo paha ka poʻe noiʻi e hiki i nā polokalamu hoʻoulu ʻiole nui ke hoʻololi i ke ʻano ʻano like ʻole i ke ʻano, akā ʻo ka mea nui i kēia manawa ʻo ka ʻae ʻana i ka hewa a hoʻoponopono.
Eia nō naʻe i loko o kahi ʻoihana i alakaʻi ʻia e ka loaʻa kālā, ʻoiaʻiʻo paha ʻo Big Pharma e ʻae i nā hewa?
ʻO ka mea pōʻino, ʻaʻole ka pane, a maopopo mai nā hemahema FDA i hala e hana nā hui lāʻau i kekahi mea i ko lākou mana e pale aku i nā hoʻomanaʻo nui. Makemake lākou e ʻōlelo "e kala mai" a uku i kahi helu liʻiliʻi o nā poho i ka poʻe i hōʻeha ʻia ma mua o ka ʻae ʻana a hoʻopau i ka pilikia nui.
Aia paha he mau haneli, a he mau kaukani lāʻau ʻino i paheʻe i ka ʻupena ma muli o nā hoʻāʻo hewa ʻole. ʻO ka hana loiloi hou a me ka hoʻomanaʻo ʻana i kēlā nui e hiki ke panakalupa i kēlā me kēia hui lāʻau lapaʻau ma ka honua - akā ʻoi aku ka nui o ke olakino o nā maʻi!
Akā he aha kāu e hana ai?
He mana ka ʻike, a ʻo ka hoʻonaʻauao ʻana i ka lehulehu a me ka poʻe nūpepa e pili ana i ka ʻepekema ma hope o kēia pukana ka hana mua. Me ka nui o ka poʻe i ʻike ʻia, hiki i ka poʻe kau kānāwai ke hoʻolohe, a hiki ke hoʻokō ʻia ka hana aupuni.
Ua pau iā ʻoe, ʻaʻole ʻoe he mana ʻole, hāʻawi ka pūnaewele i ka leo a pau i hiki ke hiki i nā miliona. E hāʻawi i kēia ʻatikala i SHARE, e haʻi i nā mea a pau āu i ʻike ai, a mai hoʻōki a hiki i ka loli ʻana.
"E lilo i hoʻololi āu e makemake ai e ʻike ma ka honua!"
Pono mākou i kāu kōkua! Lawe mākou iā ʻoe i ka nūhou uncensored no FREE, akā hiki iā mākou ke hana i kēia me ke kākoʻo o ka poʻe heluhelu pono e like me KAU! Inā manaʻoʻiʻo ʻoe i ka ʻōlelo kūʻokoʻa a hauʻoli i ka nūhou maoli, e noʻonoʻo e kākoʻo i kā mākou misionari ma lilo i kahu a i ʻole ma ka hana ʻana i kahi hāʻawi hoʻokahi wale nō ma ʻaneʻi. 20% o ALL hāʻawi ʻia nā kālā i poe kahiko!
By Richard Ahern - Ola hoʻohiolo
Hoʻokaʻaʻike: Richard@lifeline.news
Kuhiʻia:
Hōʻike Hou:
E hoʻomaopopo ' (hōʻoia hōʻoia ʻoiaʻiʻo):
- Nā helu helu hoʻomanaʻo lāʻau FDA: https://www.maylightfootlaw.com/blogs/fda-drug-recall-statistics/ [Heluhelu kūhelu]
- Deoxyribonucleic Acid (DNA): https://www.genome.gov/genetics-glossary/Deoxyribonucleic-Acid [Pūnaewele aupuni]
- Mitosis / mahele pūnaewele: https://www.nature.com/scitable/definition/mitosis-cell-division-47/ [Nā puke puke haʻawina/pūnaewele]
- ʻO ka hihia no Junk DNA: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014423/ [Nā puke puke haʻawina/pūnaewele]
- Telomeres, ka nohona, ka maʻi kanesa, a me ka ʻelemakule: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370421/ [Pepa noiʻi loiloi ʻia e nā hoa]
- ʻO ka palena Hayflick: https://embryo.asu.edu/pages/hayflick-limit#:~:text=The%20Hayflick%20Limit%20is%20a,programmed%20cell%20death%20or%20apoptosis. [Nā puke puke haʻawina/pūnaewele]
- Senescence a me ka ʻelemakule: Nā kumu, nā hopena, a me nā ala lapaʻau: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748990/ [Pepa noiʻi loiloi ʻia e nā hoa]
- Nā Mutagens Kaiapuni, Hōʻailona Kelepona a me ka Hoʻoponopono DNA: https://www.nature.com/scitable/topicpage/environmental-mutagens-cell-signalling-and-dna-repair-1090/ [Nā puke puke haʻawina/pūnaewele]
- ʻO nā telomeres ultra-long hypervariable i nā ʻiole: https://www.nature.com/articles/347400a0 [Pepa noiʻi loiloi ʻia e nā hoa]
- Bret Weinstein ma ka "The Portal" (me Eric Weinstein), Ep. #019 – Ka wānana a me ka DISC: https://www.youtube.com/watch?v=JLb5hZLw44s [Mai pololei mai ke kumu]
- Loaʻa nā telomere pōkole o nā ʻiole i loaʻa i ka nahelehele: https://pubmed.ncbi.nlm.nih.gov/11071935/ [Pepa noiʻi loiloi ʻia e nā hoa]
- ʻO ke kuhiakau hiki ke hoʻopaʻa ʻia: nā kumu evolutionary a me nā hopena hou o ke kālepa-off ma waena o ka hoʻopau ʻana i ka ʻōpū a me ka hoʻoponopono ʻana i ka ʻiʻo: https://www.gwern.net/docs/longevity/2002-weinstein.pdf [Pepa noiʻi loiloi ʻia e nā hoa]
- Alexander, P., 1966. Aia kekahi pilina ma waena o ka ʻelemakule, ka pōkole o ke ola ma ka radiation a me ka hoʻokomo ʻana o nā hoʻololi somatic?: Nā Manaʻo i ka Gerontology Hoʻokolohua. aoao 266-279. [Pepa noiʻi loiloi ʻia e nā hoa]
- Nā kāne a me nā ʻiole: E pili ana i ko lākou mau makahiki: https://pubmed.ncbi.nlm.nih.gov/26596563/ [Pepa noiʻi loiloi ʻia e nā hoa]
- Cerivastatin: https://pubchem.ncbi.nlm.nih.gov/compound/Cerivastatin [Nā puke puke haʻawina/pūnaewele]
- Nā Kūlana Lahui i ka hoʻohana ʻana i ka Statin a me nā hoʻolilo i ka heluna kanaka makua o ʻAmelika mai 2002 a i 2013: https://jamanetwork.com/journals/jamacardiology/fullarticle/2583425 [Heluhelu kūhelu]
- ʻO Rhabdomyolysis: Pathogenesis, ʻike, a me ka mālama ʻana: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365849/ [Pepa noiʻi loiloi ʻia e nā hoa]
- Nā kumu hoʻohālike wehewehe lāʻau lapaʻau o ka rhabdomyolysis pili i ka cerivastatin: https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1563-258X.2003.03029.x [Nā puke puke haʻawina/pūnaewele]
- Vioxx (rofecoxib) Nīnau a pane: https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/vioxx-rofecoxib-questions-and-answers#:~:text=Vioxx%20is%20a%20COX%2D2,3. [Pūnaewele aupuni]
- Valdecoxib: https://en.wikipedia.org/wiki/Valdecoxib [Heluhelu hou aku}
- ʻO ka maʻi maʻi ʻo Stevens-Johnson/necrolysis epidermal toxic: https://rarediseases.info.nih.gov/diseases/7700/stevens-johnson-syndrometoxic-epidermal-necrolysis [Pūnaewele aupuni]
- US v. Pfizer, Inc. – Kuʻikahi Hoʻoholo: https://www.justice.gov/usao-ma/press-release/file/1066111/download [Pepa hoʻokolokolo kūhelu]
- Rezulin: https://www.accessdata.fda.gov/drugsatfda_docs/label/1999/20720s12lbl.pdf [Pūnaewele aupuni]
- Troglitazone: https://en.wikipedia.org/wiki/Troglitazone [Heluhelu hou aku}
E hui pū me ke kūkākūkā!
Hana wau i $90 i hoʻokahi hola e hana ana mai ka home. ʻAʻole loa au i noʻonoʻo he ʻoiaʻiʻo ia i ka maikaʻi akā ke loaʻa nei kaʻu hoa pili loa i $16,000 i hoʻokahi mahina ma ka hana ʻana i kahi kamepiula, he mea kupanaha loa ia iaʻu, ua kauoha ʻo ia iaʻu e hoʻāʻo maʻalahi. Pono nā kānaka a pau e hoʻāʻo i kēia hana ma ka hoʻohana ʻana i kēia ʻatikala. http://Www.Works75.Com
ʻO kaʻu uku ma ka liʻiliʻi he $300/lā. ʻŌlelo mai koʻu hoa hana iaʻu! Pīhoihoi loa au no ka mea kōkua maoli ʻoe i ka poʻe e loaʻa nā manaʻo pehea e loaʻa kālā ai. Mahalo iā ʻoe no kou mau manaʻo a ke lana nei koʻu manaʻo e hoʻokō ʻoe i nā mea hou aʻe a loaʻa iā ʻoe nā pōmaikaʻi hou aʻe. Mahalo wau i kāu Pūnaewele Manaʻo wau e ʻike ʻoe iaʻu & manaʻo wau hiki iaʻu ke lanakila pū i kāu hāʻawi paypal.
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Hana wau i $90 i hoʻokahi hola e hana ana mai ka home. ʻAʻole loa au i noʻonoʻo he ʻoiaʻiʻo ia i ka maikaʻi akā ke loaʻa nei koʻu hoa pili loa i ka $16,000 i ka mahina ma ka hana ʻana i kahi kamepiula, he mea kupanaha loa ia iaʻu, ua kauoha ʻo ia iaʻu e hoʻāʻo maʻalahi. Pono nā kānaka a pau e hoʻāʻo i kēia hana i kēia manawa
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Loaʻa i kaʻu keikikāne he $16453/hola ma ka pūnaewele. ʻEono mahina ʻaʻole ʻo ia i hāʻawi ʻia, akā naʻe, ua lilo kāna uku i $XNUMX e hana maoli ana ma ka pūnaewele no kekahi mau hola.
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Loaʻa iaʻu ka uku ma luna o $190 i kēlā me kēia hola e hana ana mai ka home me 2 mau keiki ma ka home. ʻAʻole wau i manaʻo e hiki iaʻu ke hana akā loaʻa kaʻu hoaaloha maikaʻi ma mua o 15k i ka mahina e hana ana i kēia a ua hoʻohuli ʻo ia iaʻu e hoʻāʻo. pau ʻole ka hiki me kēia…, <(“)
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ʻO kaʻu uku hope loa he $2500 no ka hana ʻana i nā hola 12 o ka pule ma ka pūnaewele. Ua awelika koʻu hoa kaikuahine i ka 8k no nā mahina i kēia manawa a hana ʻo ia ma kahi o 30 mau hola o ka pule. ʻAʻole hiki iaʻu ke manaʻoʻiʻo i ka maʻalahi o ka hoʻāʻo ʻana. ʻO ka hiki me kēia he pau ʻole. ʻO kēia kaʻu hana >> http://www.workonline1.com
[ HUI MAI ]
Mai koʻu hoʻomaka ʻana me kaʻu ʻoihana pūnaewele loaʻa iaʻu he $90 i kēlā me kēia 15 mau minuke. ʻAʻole hiki ke manaʻoʻiʻo akā ʻaʻole ʻoe e kala iā ʻoe iho inā ʻaʻole ʻoe e nānā.
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Loaʻa ka loaʻa kālā hou i kēlā me kēia mahina mai ka home ma mua o $26k ʻoiaʻiʻo me ke kumu o ka hoʻohana ʻana i ka hana hoʻopiʻi maʻalahi a paʻi e like me ka hoihoi ma ka pūnaewele. Ua loaʻa iaʻu he $18636 mai kēia hoihoi home maʻemaʻe Hiki i nā poʻe āpau ke loaʻa kālā hou ma ka pūnaewele me ka hoʻopuka ʻole ʻana i ke kumu o ka hoʻohana ʻana o…….. https://salarybaar234.blogspot.com